Rational Design of Novel Inhibitors of INDY (I’m not dead yet) transporters:


MSc in Medicinal Chemistry

Rational Design of Novel Inhibitors of INDY (I’m not dead yet) transporters

Supervisors: Dr Aniello Palma and Dr Christopher Mulligan

A Masters opportunity is available in the field of medicinal chemistry in the groups of Dr Aniello Palma and Dr Christopher Mulligan.

The objective of this exciting project is to rationally design, synthesise and characterize a new class of inhibitors for divalent anion sodium symporter (DASS) transporter proteins which are excellent therapeutic targets for cancer and age-related metabolic diseases. These inhibitors synthesised in the Palma lab (School of Physical Sciences) will be tested in the Mulligan lab (Bioscience School).

The successful candidate will be based at the University of Kent’s Canterbury campus, and work under the joint supervision of Dr Aniello Palma and Dr Christopher Mulligan. This exciting project is deeply interdisciplinary in nature therefore, the successful candidate will receive well-rounded training in synthetic organic chemistry, drug design and in a number of molecular biology techniques with ample opportunity for personal development.

This position is due to start in September 2019.

Entry requirements and fees: Applicants should have/expect to obtain, a first or upper second class honours degree (or equivalent) in Chemistry or a related subject. This is a self-funded position and candidates will be liable for tuition fees at the standard rate (£4,327 for UK/EU candidates).

Webpage(s): www.palmaresearchgroup.com https://www.kent.ac.uk/biosciences/people/1034/mulligan-christopher

Contact: For further information or informal enquiries, please contact Dr Aniello Palma (a.palma@kent.ac.uk) or Dr Christopher Mulligan (c.mulligan@kent.ac.uk)

How to Apply: To apply please go to https://www.kent.ac.uk/courses/postgraduate/18/chemistry

You will need to apply through the online application form on the main University website. Please note that you will be expected to provide personal details, education and employment history and supporting documentation (Curriculum Vitae, transcript of results, two academic references).

Deadline Date for Applications: Open call